Multiple Sclerosis is an autoimmune disease that affects about 400,000 people in the US. Twice as many women as men are diagnosed with the disease, with the normal age of diagnosis being in around 35. Whilst Ms doesn’t appear to affect infertility, some drugs used to treat the MS can affect fertility and it appears that infertility treatment could affect MS.
According to a study published this month in the Annals of Neurology, assisted reproduction technology (ART) increases the activity of Multiple Sclerosis (MS). The study showed that 3 out of 4 women experienced increased MS activity following ART.
ART infertility treatments involve manipulating the patient’s hormones to optimize their chances of conceiving. However, increases in the same hormones, have been found to influence the course that an autoimmune disorder may take.
This small study of 16 people who had 26 rounds of ART was conducted over a 5 year period. Compared to women with similar disease history who had not had fertility treatment, the women who had had ART were seven times more likely to experience a flare in symptoms and 9 times more likely to experience increased disease activity. 3 out of 4 of the women who had flares experienced new MS symptoms, and 1 in 4 experienced worsening of their existing symptoms.
Another study, conducted in France, found a 58% increase in relapses in the three month period following the fertility treatment, compared to before treatment. Patients were also more likely to experience new or enlarged T2 and gadolinium-enhancing lesions following ART.
Because of the link between hormones and autoimmune disorder pathogenesis, it is likely that the raised levels of estrogen following this infertility treatment can stimulate the disease. Both of these studies showed that the risk was only greater in women whose hormone production had been stimulated for fertility treatment, but without success. Those who had ART and fell pregnant did not see a change in their condition.
Whilst women with MS should consider the effects that having fertility treatment could have on the short term course of their disease, it is not believed that fertility treatment or child birth have long term effects on the severity or course of the disease.
At CCSVI Mexico we are able to treat 90% if MS cases by treating the cause of their disease, Chronic Cerebrospinal Venous Insufficiency. It has been shown that CCSVI can cause iron to leak into the Central Nervous System, leaving the lesions that cause MS symptoms. By using balloon angioplasty to expand the narrowed veins, we are able to increase blood flow and alleviate the symptoms and progression of the disease.
For more information about how we can help you, contact us today.