Age and Gender Affect The Course of MS

Late Onset MSA new study, published in the Multiple Sclerosis Journal explores the link betwen the likelihood of developing progressive MS in relation to your age and gender. The average age of onset of MS is between 30 and 33 years old, with the average age of diagnosis being 37. Fewer than 10% of MS cases are diagnosed over the age of 50. The research aimed to see if the age of onset and diagnosis may give an indication of the likely course that the MS will take.

The study, conducted by researchers in Boston, set out to study the incidence and potential outcomes of adult-onset multiple sclerosis (AOMS) in comparison to late onset multiple sclerosis (LOMS).  Researchers looked at the demographic characteristics, including age and gender, of 4273 people with MS. They compared these details against the characteristics of the disease in each individual to establish the likely course that MS will take after diagnosis according to the demographic of the patient. They also looked at the time it took from onset of the disease to reaching and Expanded Disability Status Scale (EDSS) of 6, which means that they need assistance to walk.

The findings

The research found that only 7.96 of the participants had onset of MS after age 50, with a further 1.33% being diagnosed over the age of 60.  Of the participants, those diagnosed later, (over the age of 50) were more likely to develop progressive MS, with incidence of progressive MS being 25.6% for those aged 50-60 compared to 6.9% in people diagnosed before they were 50 and 35.1% for those diagnosed over the age of 60.

In people diagnosed under the age of 50, men progressed to EDSS 6.0 more quickly than women, however in those diagnosed after they were 50 the rate of progression was the same for men and women. This indicates that after menopause the progression for women is accelerated.

MS is a disease of varying severity, with a wide range of symptoms. Understanding how these symptoms manifest themselves and the course that the disease is likely to take is beneficial to doctors and patients alike, both before and after diagnosis.

MS is also a progressive disease, which means that it will continue to get worse. Although there are drugs available that can help to control the condition, it is considered to be incurable at this stage. However, it is thought that many people’s MS symptoms are actually caused by a narrowing of the veins leaving the brain, a condition known as CCSVI which affects the central nervous system in much the same way as MS. Unlike MS, CCSVI is a treatable condition.

At CCSVI Mexico we have treated many patients with astounding success. If you have been diagnosed with MS, whatever your age, contact us today to see if we can help you.

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